8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and early biomarker of oxidative tissue damage. It serves as an immunogen for mAb8B3, detecting DNA modifications. Elevated urinary levels occur in inflammatory disease models. Used in studies for inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation.
- Inflammation-related DNA halogenated adduct.
- Early biomarker of inflammation-induced oxidative tissue damage.
- Immunogen for mAb8B3 monoclonal antibody.
- Urinary levels increase in inflammatory disease models.
- Applications in inflammatory diseases, diabetes, hepatocellular carcinoma, UV-B induced skin inflammation.
- High, specific cross-reactivity with mAb8B3 in competitive indirect ELISA.